Discussing BRCA 1&2 Gene Mutations, the Risk of Breast Cancer and the Risk of Bias in the Research.

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If you have been told you have the BRCA1/2 gene mutation that “causes” breast cancer, should you have your breasts or ovaries removed? 

What does the evidence say about this “prophylactic” procedure, oophorectomy? Sadly the truth is not what women are lead to believe.   

Oophorectomy is a procedure to remove the ovaries of women. This procedure is done or suggested often when women are told they have the BRCA gene mutations, but does this surgery improve your likelihood of living longer? 

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Resources / References:

Cancer experts laud Angelina Jolie’s decision to remove ovaries

http://www.reuters.com/article/us-people-angelinajolie-cancer/cancer-experts-laud-angelina-jolies-decision-to-remove-ovaries-idUSKBN0MK0PW20150324

Breast cancer risk after salpingo-oophorectomy in healthy BRCA1/2 mutation carriers: revisiting the evidence for risk reduction.

https://www.ncbi.nlm.nih.gov/pubmed/25788320

Premature menopause or early menopause: long-term health consequences.

https://www.ncbi.nlm.nih.gov/pubmed/19733988

Survival patterns after oophorectomy in premenopausal women: a population-based cohort study

https://www.ncbi.nlm.nih.gov/pubmed/17012044

Why Genetic Tests Don’t Help Doctors Predict Your Risk of Disease

http://healthland.time.com/2012/05/25/why-genetic-tests-dont-help-doctors-predict-your-risk-of-disease/

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